Made in USA 

Made in the USA 

Not tested on animals 

Not Tested on Animals 

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For Smooth, Soft Feet and Heels without Scraping
Callex Ointment exfoliates and moisturizes dry, cracked feet and heels.  Its patented, exfoliating enzymes are protease (subtilisin) and aminopeptidase.  These enzymes are mixed with the highest grade of petrolatum USP and natural peppermint oil.  This formulation selectively exfoliates only dry, cracked and flaking skin on heels, soles and toes, while moisturizing the foot by preventing dehydration through the skin.
Callex has been sold in pharmacies nation-wide since 2005.  Clinical efficacy and safety studies were conducted in 2004 and can be viewed by clicking the link to the right.  Results after 4 weeks of use for dryness and cracking showed a highly significant improvement on both measures.  A Repeated Insult Patch Test indicated no potential for dermal irritation or allergic contact sensitization. The benefits of using Callex Ointment can be summarized as follows:

  • Exfoliates with enzymes, not harsh acids
  • Keeps feet soft and supple once exfoliation is complete
  • Paraben-Free - Preservative-Free – Alcohol-Free (won’t dry skin)
  • Safe for Diabetics with Healthy feet
  • Fragranced with natural peppermint oil – refreshing scent
  • The 1.75 oz. jar is a 1 – 2 month supply, depending on coverage

Money Back Guaranteed to your patients by Xenna Corporation.

$14.99, 1.75 oz. jar

Before and After Pictures

More Before and After Photos

Write your own product review here.

This ointment is different, It works!

March 08, 2017

Anonymous Blogger

We have used other lotions for dry/cracked heels, but, this ointment is different. It works. We have tried exfoliated and lotion and while it does make them feel less painful, they were still dry and slightly cracked. With Callex we have been using it twice a day for several days and this morning they were smooth and soft like a babies behind. It is awesome. All that we did was wash our feet, applied ointment and donned a pair of socks (to avoid getting the ointment on the floor). This soaked right and created unbelievable smoothness. Relieving!  Ginae Reviews, book and product reviews, sans the technical jargon.

Results you can see

March 07, 2017

Robert R., Springfield, VA | review with repeat order at

Excellent product.  Yields real results that you can see.

Works miracles and quickly.

March 01, 2017

R. W., Granville, OH

A big part of the solution to my diabetic foot….  Works miracles and quickly.

Best ever used!

February 08, 2017

Female, by email, San Antonio, TX

The best care for my feet I ever used.

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Cracked, Dry Feet?

Callex Ointment thins and softens hardened skin and exfoliates dry, cracked heels. Its patented enzymes selectively exfoliate only dry, cracked, thickened and flaky skin while its naturally-derived base retains skin moisture.

Callex is free of irritating acids, mineral oil, colorants, parabens and lanolin. It is also effective for hardened skin caused by sport, brace or work-related footwear.

Dermatologist-tested, Callex Ointment is fast-acting, money-back guaranteed and lightly fragranced with refreshing peppermint oil. With daily use, complete exfoliation and/or softening takes between 2 and 4 weeks, depending on the amount of dry or thickened skin on your foot.

The 1.75 oz. jar is a one to two month supply.

Directions for Use

Thickened or Dry, Cracked Feet

  1. Apply directly to rough, dry or hardened areas of the foot twice daily
  2. Rub area with warm, wet washcloth between applications
  3. Expect results in 3 to 12 days – complete exfoliation in 15 to 30 days.


Petrolatum, U.S.P., protease (subtilisin), aminopeptidase, peppermint oil.


  • For external use only
  • Keep out of reach of children
  • Do not use on irritated, infected or open skin.
  • Keep away from eye areas and avoid eye contact. If eye contact occurs, flush with cool water immediately.
  • Wash hands after use.


How long will it take to see a difference on my heels?

Your heels and feet will be softer in a few days and visibly smoother within a week. It will take 2 to 4 weeks for complete exfoliation and soft, supple skin. Once your heels are no longer dry or cracked, apply CalleX 2 or 3 times a week at night for maintenance.

Can I wear socks over my feet when I use CalleX?

Yes, Callex Ointment will not stain your socks and will actually work faster if you wear “footsies” or short tennis socks to bed after your evening application while sleeping.

How can I make CalleX work fastest?

Always apply CalleX after bathing when your skin is softer. Secondly rub your dry, rough areas with a warm, wet washcloth prior to applying more CalleX. This will loosen any dead skin and speed results. Be sure to wash hands after using CalleX to avoid accidental eye contact.